Original language | English |
---|---|
Pages (from-to) | 1576-1589 |
Number of pages | 14 |
Journal | Addiction Biology |
Volume | 22 |
Issue number | 6 |
DOIs | |
Publication status | Published (VoR) - Nov 2017 |
Keywords
- Abstinence
- naltrexone
- reward
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In: Addiction Biology, Vol. 22, No. 6, 11.2017, p. 1576-1589.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Acute naltrexone does not remediate fronto-striatal disturbances in alcoholic and alcoholic polysubstance-dependent populations during a monetary incentive delay task
AU - ICCAM Consortium
AU - Nestor, Liam J.
AU - Murphy, Anna
AU - McGonigle, John
AU - Orban, Csaba
AU - Reed, Laurence
AU - Taylor, Eleanor
AU - Flechais, Remy
AU - Paterson, Louise M.
AU - Smith, Dana
AU - Bullmore, Edward T.
AU - Ersche, Karen D.
AU - Suckling, John
AU - Tait, Roger
AU - Elliott, Rebecca
AU - Deakin, Bill
AU - Rabiner, Ilan
AU - Lingford-Hughes, Anne
AU - Nutt, David J.
AU - Sahakian, Barbara
AU - Robbins, Trevor W.
N1 - Funding Information: The authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This article presents independent research funded by the MRC as part of their addiction initiative (grant number G1000018). GSK kindly funded the functional and structural MRI scans that took place at the London site for this study. ICCAM platform collaborators: David Nutt, Anne Lingford-Hughes, Louise Paterson, John McGonigle, Remy Flechais, Csaba Orban, William Deakin, Rebecca Elliott, Anna Murphy, Eleanor Taylor, Trevor Robbins, Karen Ersche, Ed Bullmore, John Suckling, Dana Smith, Laurence Reed, Filippo Passetti, Luca Faravelli, David Erritzoe, Inge Mick, Nicola Kalk, Adam Waldman, Liam Nestor, Shankar Kuchibatla, Venkataramana Boyapati, Antonio Metastasio, Yetunde Faluyi, Emilio Fernandez-Egea, Sanja Abbott, Barbara Sahakian, Valerie Voon, Ilan Rabiner. The research was carried out at the NIHR/Wellcome Trust Imperial Clinical Research Facility, the NIHR/Wellcome Trust Cambridge Research Facility and Clinical Trials Unit at Salford Royal NHS Foundation Trust, and is supported by the North West London, Eastern and Greater Manchester NIHR Clinical Research Networks. This article presents independent research funded by the Medical Research Council and supported by the NIHR CRF at Imperial College Healthcare NHS Trust. The views expressed are those of the author(s) and not necessarily those of the Medical Research Council, the NHS, the NIHR or the Department of Health. The authors wish to thank research assistants Claire Whitelock, Heather Agyepong, Rania Christoforou and Natalie Cuzen for their help with data collection, Dr Sharon Morein-Zamir for her help with data extraction, MR physicist Rex Newbould and MR technician, Jonathan Howard for their assistance with MR acquisition and task setup. The authors also wish to thank their recruitment partners; Imperial College Healthcare NHS Trust, Central and North West London NHS Trust, Camden and Islington NHS Trust, Cambridge University Hospitals NHS Foundation Trust, Norfolk and Suffolk NHS Foundation Trust, Cambridge and Peterborough NHS Foundation Trust, South Staffordshire and Shropshire NHS Foundation Trust, Manchester Mental Health NHS and Social Care Trust, Greater Manchester West NHS Foundation Trust, Pennine Care NHS Foundation Trust, Salford Royal NHS Foundation Trust, Addaction, Foundation 66 and CRI (Crime Reduction Initiative). Funding Information: The authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This article presents independent research funded by the MRC as part of their addiction initiative (grant number G1000018). GSK kindly funded the functional and structural MRI scans that took place at the London site for this study. Funding Information: William Deakin currently advises or carries out research funded by Autifony, Sunovion, Lundbeck, AstraZeneca and Servier. All payment is to the University of Manchester. Funding Information: ICCAM platform collaborators: David Nutt, Anne Lingford-Hughes, Louise Paterson, John McGonigle, Remy Flechais, Csaba Orban, William Deakin, Rebecca Elliott, Anna Murphy, Eleanor Taylor, Trevor Robbins, Karen Ersche, Ed Bullmore, John Suckling, Dana Smith, Laurence Reed, Filippo Passetti, Luca Faravelli, David Erritzoe, Inge Mick, Nicola Kalk, Adam Waldman, Liam Nestor, Shankar Kuchibatla, Venkataramana Boyapati, Antonio Metastasio, Yetunde Faluyi, Emilio Fernandez-Egea, Sanja Abbott, Barbara Sahakian, Valerie Voon, Ilan Rabiner. The research was carried out at the NIHR/Wellcome Trust Imperial Clinical Research Facility, the NIHR/Wellcome Trust Cambridge Research Facility and Clinical Trials Unit at Salford Royal NHS Foundation Trust, and is supported by the North West London, Eastern and Greater Manchester NIHR Clinical Research Networks. This article presents independent research funded by the Medical Research Council and supported by the NIHR CRF at Imperial College Healthcare NHS Trust. The views expressed are those of the author(s) and not necessarily those of the Medical Research Council, the NHS, the NIHR or the Department of Health. The authors wish to thank research assistants Claire Whitelock, Heather Agyepong, Rania Christoforou and Natalie Cuzen for their help with data collection, Dr Sharon Morein-Zamir for her help with data extraction, MR physicist Rex Newbould and MR technician, Jonathan Howard for their assistance with MR acquisition and task setup. The authors also wish to thank their recruitment partners; Imperial College Healthcare NHS Trust, Central and North West London NHS Trust, Camden and Islington NHS Trust, Cambridge University Hospitals NHS Foundation Trust, Norfolk and Suffolk NHS Foundation Trust, Cambridge and Peterborough NHS Foundation Trust, South Staffordshire and Shropshire NHS Foundation Trust, Manchester Mental Health NHS and Social Care Trust, Greater Manchester West NHS Foundation Trust, Pennine Care NHS Foundation Trust, Salford Royal NHS Foundation Trust, Addaction, Foundation 66 and CRI (Crime Reduction Initiative). Publisher Copyright: © 2016 Society for the Study of Addiction
PY - 2017/11
Y1 - 2017/11
KW - Abstinence
KW - naltrexone
KW - reward
UR - http://www.scopus.com/inward/record.url?scp=84986332700&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84986332700&partnerID=8YFLogxK
U2 - 10.1111/adb.12444
DO - 10.1111/adb.12444
M3 - Article
C2 - 27600363
AN - SCOPUS:84986332700
SN - 1355-6215
VL - 22
SP - 1576
EP - 1589
JO - Addiction Biology
JF - Addiction Biology
IS - 6
ER -