Charge delocalisation and the design of novel mastoparan analogues: Enhanced cytotoxicity and secretory efficacy of [Lys5, Lys 8, Aib10]MP

Sarah Jones; John Howl

doi:10.1016/j.regpep.2004.04.015

Charge delocalisation and the design of novel mastoparan analogues: Enhanced cytotoxicity and secretory efficacy of [Lys⁵, Lys ⁸, Aib¹⁰]MP

Sarah Jones, John Howl^*

^*Corresponding author for this work

University of Wolverhampton

Research output: Contribution to journal › Article › peer-review

29 Citations (SciVal)

Original language	English
Pages (from-to)	121-128
Number of pages	8
Journal	Regulatory Peptides
Volume	121
Issue number	1-3
DOIs	https://doi.org/10.1016/j.regpep.2004.04.015
Publication status	Published (VoR) - 15 Sept 2004

Funding

The Wellcome Trust provided financial support for this work.

Funders	Funder number
Wellcome Trust

Keywords

α-aminoisobutyric acid
β-Hexoseaminidase
9- fluorenylmethoxycarbonyl
Aib
DMEM
Dulbecco's modified Eagle medium
ERK
ERK1/2 phosphorylation
extracellular receptor-stimulated kinase
Fmoc
MBHA
RBL-2H3 mast cell
U373MG astrocytoma

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10.1016/j.regpep.2004.04.015

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title = "Charge delocalisation and the design of novel mastoparan analogues: Enhanced cytotoxicity and secretory efficacy of [Lys5, Lys 8, Aib10]MP",

keywords = "α-aminoisobutyric acid, β-Hexoseaminidase, 9- fluorenylmethoxycarbonyl, Aib, DMEM, Dulbecco's modified Eagle medium, ERK, ERK1/2 phosphorylation, extracellular receptor-stimulated kinase, Fmoc, MBHA, RBL-2H3 mast cell, U373MG astrocytoma",

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T2 - Enhanced cytotoxicity and secretory efficacy of [Lys5, Lys 8, Aib10]MP

AU - Jones, Sarah

AU - Howl, John

PY - 2004/9/15

Y1 - 2004/9/15

KW - α-aminoisobutyric acid

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KW - 9- fluorenylmethoxycarbonyl

KW - Aib

KW - DMEM

KW - Dulbecco's modified Eagle medium

KW - ERK

KW - ERK1/2 phosphorylation

KW - extracellular receptor-stimulated kinase

KW - Fmoc

KW - MBHA

KW - RBL-2H3 mast cell

KW - U373MG astrocytoma

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Charge delocalisation and the design of novel mastoparan analogues: Enhanced cytotoxicity and secretory efficacy of [Lys⁵, Lys ⁸, Aib¹⁰]MP

Funding

Keywords

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