Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis

Bárbara Matos, Daniela Patrício, Magda C. Henriques, Maria J. Freitas, Rui Vitorino, Iola F. Duarte, John Howl, Paula A. Oliveira, Fernanda Seixas, José A. Duarte, Rita Ferreira, Margarida Fardilha*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    5 Citations (SciVal)
    Original languageEnglish
    Pages (from-to)311-327
    Number of pages17
    JournalCellular Oncology
    Volume44
    Issue number2
    DOIs
    Publication statusPublished (VoR) - Apr 2021

    Funding

    We are thankful to the Portuguese Foundation for Science and Technology (FCT), the European Union, QREN, FEDER and COMPETE for funding the Institute of Biomedicine - iBiMED (UID/BIM/04501/2013, POCI-01-0145-FEDER-007628 and UID/BIM/04501/2019), Organic Chemistry, Natural and Agro-food Products - QOPNA (UID/QUI/00062/2013), Aveiro Institute of Materials - CICECO (UID/CTM/50011/2019), Center for the Research and Technology of Agro-Environmental and Biological Sciences - CITAB (UID/AGR/04033/2019) and Research Centre in Physical Activity, Health and Leisure - CIAFEL (UID/DTP/00617/2019) research units, and the research project RUNawayPCa (POCI-01-0145-FEDER-006958 and PTDC/DTP-DES/6077/2014). We also acknowledge the Portuguese National NMR (PTNMR) Network, supported by FCT funds, and the European Union Framework Programme for Research and Innovation HORIZON 2020, under the TEAMING Grant agreement No 739572 - The Discoveries CTR. We are also thankful to Celeste Resende for assistance in sample preparations for histological analyses.

    FundersFunder number
    Aveiro Institute of Materials
    CITABUID/AGR/04033/2019
    Center for the Research and Technology of Agro-Environmental and Biological Sciences
    Institute of Biomedicine - iBiMEDUID/QUI/00062/2013, UID/BIM/04501/2019, POCI-01-0145-FEDER-007628, UID/BIM/04501/2013
    QREN
    Centro de Investigação em Materiais Cerâmicos e CompósitosUID/CTM/50011/2019
    Horizon 2020 Framework Programme739572
    European Commission
    Fundação para a Ciência e a Tecnologia
    Horizon 2020
    Programa Operacional Temático Factores de Competitividade
    Centro de Investigação em Actividade Física, Saúde e LazerUID/DTP/00617/2019, POCI-01-0145-FEDER-006958, PTDC/DTP-DES/6077/2014

      Keywords

      • DNA repair
      • Exercise training
      • Metabolism
      • Oxidative stress
      • Prostate cancer
      • Testicular function

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