CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses

Irmgard U. Haussmann; Yanying Wu; Mohanakarthik P. Nallasivan; Nathan Archer; Zsuzsanna Bodi; Daniel Hebenstreit; Scott Waddell; Rupert Fray; Matthias Soller

doi:10.1038/s41467-022-28549-5

CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses

Irmgard U. Haussmann, Yanying Wu, Mohanakarthik P. Nallasivan, Nathan Archer, Zsuzsanna Bodi, Daniel Hebenstreit, Scott Waddell, Rupert Fray, Matthias Soller

Research output: Contribution to journal › Article › peer-review

21 Citations (SciVal)

Original language	English
Article number	1209
Journal	Nature Communications
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41467-022-28549-5
Publication status	Published (VoR) - Dec 2022

Funding

We thank S. Brogna, C. Samakovlis, B. Suter, J.-Y. Roignant, M. Ramaswami, FlyORF and the Bloomington and Kyoto stock centers for fly lines, S. Brogna, D. Kopytova, P. Lasko and the Developmental Studies Hybridoma Bank for antibodies, S. Brogna for an oligo(dT) probe, the University of Cambridge Department of Genetics Fly Facility for injections, BacPac for DNA clones, E. Zaharieva for help with stainings, D. Balacco and F. Stappers for help with artwork, and B. Muller and R. Michell for comments on the manuscript. MS is funded by the BBSRC (BB/R002932/1) and the Leverhulme Trust, RGF from BBSRC (BB/R001715/1), DH from WISB, a BBSRC/EPSRC Synthetic Biology Research Centre (BB/M017982/1) and BBSRC (BB/L006340/1), and S.W. by a Wellcome Principal Research Fellowship (200846/Z/16/Z) and an ERC Advanced Grant (789274). NA is a Nottingham Research Fellow funded by the University of Nottingham.

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title = "CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses",

author = "Haussmann, \{Irmgard U.\} and Yanying Wu and Nallasivan, \{Mohanakarthik P.\} and Nathan Archer and Zsuzsanna Bodi and Daniel Hebenstreit and Scott Waddell and Rupert Fray and Matthias Soller",

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T1 - CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses

AU - Haussmann, Irmgard U.

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AU - Archer, Nathan

AU - Bodi, Zsuzsanna

AU - Hebenstreit, Daniel

AU - Waddell, Scott

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AU - Soller, Matthias

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CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses

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