Cost-effectiveness of negative-pressure wound therapy in adults with severe open fractures of the lower limb: Evidence from the WOLLF randomized controlled trial

S. Petrou*, B. Parker, J. Masters, J. Achten, J. Bruce, S. E. Lamb, N. Parsons, M. L. Costa, Keith Willett, Damian Griffin, Steven Jeffery, Jill Arrowsmith, Gorav Datta, Mick Dennison, Mark Farrar, Peter Giannoudis, Andrew Gray, Philip Henman, Peter Hull, Umraz KhanCharlotte Lewis, David Loveday, Jitendra Mangwani, Andrew McAndrew, Damian McClelland, Mike McNicholas, David Noyes, Ben Ollivere, Ian Pallister, Keith Porter, Manoj Ramachandran, Rory Rickard, Benedict Rogers, Hemant Sharma, Adel Tavakkolizadeh, Jonathan Young

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    24 Citations (SciVal)
    Original languageEnglish
    Pages (from-to)1392-1401
    Number of pages10
    JournalBone and Joint Journal
    Volume101-B
    Issue number11
    DOIs
    Publication statusPublished (VoR) - 2019

    Funding

    S. Petrou, J. Achten, J. Bruce, S. E. Lamb, N. Parsons, and M. L. Costa report an institutional grant (paid to The University of Warwick) from the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (project number 10/57/20), related to this study. M. L. Costa is also employed by the University of Oxford, which received institutional research fund grants from the NIHR, the European Union (EU), and the Royal College of Surgeons England and Industry. S. Petrou, J. Achten, J. Bruce, S. E. Lamb, N. Parsons, and M. L. Costa report an institutional grant (paid to The University of Warwick) from the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (project number 10/57/20), related to this study. M. L. Costa is also employed by the University of Oxford, which received institutional research fund grants from the NIHR, the European Union (EU), and the Royal College of Surgeons England and Industry. No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. The data used for this study is from the Wound Management of Open Lower Limb Fractures (WOLLF) randomized controlled trial, which was funded by the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (project number 10/57/20) and was supported by the NIHR Oxford Biomedical Research Centre. The funder has not been involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript nor in the decision to submit the manuscript for publication. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The two main commercial entities in this sector funded the excess treatment costs of the negative-pressure wound therapy (NPWT) dressings but had no part in the design, conduct, or reporting of the trial. The data used for this study is from the Wound Management of Open Lower Limb Fractures (WOLLF) randomized controlled trial, which was funded by the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (project number 10/57/20) and was supported by the NIHR Oxford Biomedical Research Centre. The funder has not been involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript nor in the decision to submit the manuscript for publication. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The two main commercial entities in this sector funded the excess treatment costs of the negative-pressure wound therapy (NPWT) dressings but had no part in the design, conduct, or reporting of the trial.

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