Original language | English |
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Article number | k1675 |
Journal | British Medical Journal |
Volume | 361 |
DOIs | |
Publication status | Published (VoR) - 2018 |
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In: British Medical Journal, Vol. 361, k1675, 2018.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia
T2 - Randomised controlled trial
AU - DAPA Trial Investigators
AU - Lamb, Sarah E.
AU - Sheehan, Bart
AU - Atherton, Nicky
AU - Nichols, Vivien
AU - Collins, Helen
AU - Mistry, Dipesh
AU - Dosanjh, Sukhdeep
AU - Slowther, Anne Marie
AU - Khan, Iftekhar
AU - Petrou, Stavros
AU - Lall, Ranjit
AU - Alleyne, S.
AU - Hennings, S.
AU - Griffiths, F.
AU - Bridgewater, S.
AU - Eyre, E.
AU - Finnegan, S.
AU - Hall, L.
AU - Hall, P.
AU - Johnson, H.
AU - Kaur, G.
AU - Langdon, L.
AU - Lyle, S.
AU - Lowe, J.
AU - Mathews, S.
AU - Millichap, J.
AU - Nussbaum, J.
AU - On-Kar, I.
AU - Ritchie, C.
AU - Russell, V.
AU - Scott, G.
AU - Shore, S.
AU - Spanjers, K.
AU - Stonehewer, L.
AU - Thorogood, M.
AU - Todd, J.
AU - Ullah, A.
AU - Waters, H.
AU - Woods, L.
AU - Withers, E.
AU - Zeh, P.
AU - Bond, A.
AU - Brown, D.
AU - Byrne, C.
AU - McShane, R.
AU - Thomas, N.
AU - Thompson, J.
AU - Dransfield, C.
AU - Le Frenais, F.
AU - Brooke, J.
N1 - Funding Information: DAPA Trial Team: S Alleyne, S Hennings, F Griffiths, S Bridgewater, E Eyre, S Finnegan, L Hall, P Hall, H Johnson, G Kaur, L Langdon, S Lyle, J Lowe, S Mathews, J Millichap, J Nussbaum, I On-kar, C Ritchie, V Russell, G Scott, S Shore, K Spanjers, L Stonehewer, M Thorogood, J Todd, A Ullah, H Waters, L Woods, E Withers, P Zeh, A Bond, D Brown, C Byrne, R McShane, N Thomas, J Thompson, C Dransfield, F Le Frenais, C Hall, O Rye, R Carson, M Clarke, H Eaton, H Ellis, A Farrand, S Gardner, C Harducas, L Rigby, J Wilson, L Hill, L Johnson, L Lord, L Johnson, T Qassam, S Sadier, A Shipman, L South, J Statham, J Tomkins, D Weaver, B Coope, D Craddock, A Johal, J Lee, J Lindsay, J Tucker, R Vanderputt, V Cross, G Glithens-Mather, L Martin, C O’Reilly, E Rogers, R Sheridan, K Birtwell, J Brooke, A Davis, C Hinze, S Hussain, A Kennedy, H Mistry, R Noble, R Norton, E Oughton, V Sherwin, P Tinker, D Glancey, H Karrin, M Marudkar, G Borley, T Crisp, P Koranteng, A Lovesy, S Vogel, B Browne, L Colbourn, A Feast, E Hanratty, R Legerd, R Niland-Smith, T Sullivan, T Sullivan, A Streater, H St Roas, M Anderton, R Blake, K Brown, S Marriott, S Simpson, A Thornhill, L Colbourn, F Dawe, T Kuruvilla, L Moore, R Niland-Smith, M Phillips, G Riley, and A Uthup Contributors: SEL (chief investigator): conceived and designed the study and had overall responsibility for the study design and delivery. She is the guarantor. DM did the statistical analysis. NA developed and implemented the intervention and was training and quality assurance lead for the intervention. SD was responsible for the trial logistics and management, and writing and reviewing of the manuscript. IK was responsible for the economic analysis of the trial. RL is a grant holder and was responsible for the statistical analysis. HC was responsible for recruitment and guidance on strategies for recruitment and testing procedures. AMS is a grant holder and lead ethicist and provided the framework for consent and advice and guidance on ethical issues during the trial. VN was responsible for trial management and was the recruitment lead and was responsible for training and quality assurance. SP is a grant holder and was responsible for the economic analysis and writing and reviewing of the manuscript. BS was responsible for study design and conduct, clinical responsibility, and writing and reviewing of the manuscript. All authors have contributed to drafting the manuscript and approving the final version. The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted. Funding: This trial was funded by the National Institute for Health Research (NIHR Health Technology Assessment programme 09/80/04) and received additional support from the NIHR Local Clinical Research Networks and NIHR Oxford CLAHRC and Biomedical Research Centre. NIHR funded the study. It developed a commissioning brief but had no role in the study design, data acquisition, analysis, or manuscript preparation. The chief investigator (SEL) assumes overall responsibility for the data in the manuscript. All named investigators had full access to the trial dataset. There are no contractual agreements that limit access for investigators. Companies and the sponsor (University of Warwick) had no role in the funding, design, analysis, or interpretation. The views expressed are those of the authors and are not an official view of the institutions or funders. Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: no support from any organisation for the submitted work, other than funding arrangements for the trial described in body of the text; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work. Ethical approval: This study was approved by national ethics review committees (REC No 11/SW/0232) and research governance departments in each organisation. Publisher Copyright: © 2018 Published by the BMJ Publishing Group Limited.
PY - 2018
Y1 - 2018
UR - http://www.scopus.com/inward/record.url?scp=85047242102&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047242102&partnerID=8YFLogxK
U2 - 10.1136/bmj.k1675
DO - 10.1136/bmj.k1675
M3 - Article
C2 - 29769247
AN - SCOPUS:85047242102
SN - 0959-8146
VL - 361
JO - British Medical Journal
JF - British Medical Journal
M1 - k1675
ER -