Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility

Joana Vieira Silva; Maria João Freitas; Joana Santiago; Sarah Jones; Sofia Guimarães; Srinivasan Vijayaraghavan; Steven Publicover; Giorgio Colombo; John Howl; Margarida Fardilha

doi:10.1016/j.fertnstert.2020.08.013

Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility

Joana Vieira Silva, Maria João Freitas, Joana Santiago, Sarah Jones, Sofia Guimarães, Srinivasan Vijayaraghavan, Steven Publicover, Giorgio Colombo, John Howl, Margarida Fardilha^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Citations (SciVal)

Original language	English
Pages (from-to)	348-362
Number of pages	15
Journal	Fertility and Sterility
Volume	115
Issue number	2
DOIs	https://doi.org/10.1016/j.fertnstert.2020.08.013
Publication status	Published (VoR) - Feb 2021

Funding

Supported by Fundo Europeu de Desenvolvimento Regional funds through the “ Programa Operacional Competitividade e Internacionalização COMPETE 2020 ,” national funds through the Fundação para a Ciência e Tecnologia ( PTDB/BBB-BQB/3804/2014 ), iBiMED ( UIDB/04501/2020 and POCI-01-0145-FEDER-007628 ), and an individual grant from Fundação para a Ciência e Tecnologia to J.V.S.( SFRH/BPD/123155/2016 ).

Funders	Funder number
Fundação para a Ciência e a Tecnologia	SFRH/BPD/123155/2016, POCI-01-0145-FEDER-007628, UIDB/04501/2020, PTDB/BBB-BQB/3804/2014
European Regional Development Fund

Keywords

male contraception
PP1-disrupting peptides
protein phosphatase 1
protein-protein interactions
Sperm motility

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10.1016/j.fertnstert.2020.08.013

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title = "Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility",

keywords = "male contraception, PP1-disrupting peptides, protein phosphatase 1, protein-protein interactions, Sperm motility",

author = "Silva, {Joana Vieira} and Freitas, {Maria Jo{\~a}o} and Joana Santiago and Sarah Jones and Sofia Guimar{\~a}es and Srinivasan Vijayaraghavan and Steven Publicover and Giorgio Colombo and John Howl and Margarida Fardilha",

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year = "2021",

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doi = "10.1016/j.fertnstert.2020.08.013",

language = "English",

volume = "115",

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T1 - Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility

AU - Silva, Joana Vieira

AU - Freitas, Maria João

AU - Santiago, Joana

AU - Jones, Sarah

AU - Guimarães, Sofia

AU - Vijayaraghavan, Srinivasan

AU - Publicover, Steven

AU - Colombo, Giorgio

AU - Howl, John

AU - Fardilha, Margarida

PY - 2021/2

Y1 - 2021/2

KW - male contraception

KW - PP1-disrupting peptides

KW - protein phosphatase 1

KW - protein-protein interactions

KW - Sperm motility

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U2 - 10.1016/j.fertnstert.2020.08.013

DO - 10.1016/j.fertnstert.2020.08.013

M3 - Article

C2 - 32977940

AN - SCOPUS:85091496436

SN - 0015-0282

VL - 115

SP - 348

EP - 362

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 2

ER -

Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility

Funding

Keywords

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