| Original language | English |
|---|---|
| Pages (from-to) | 1990-1998 |
| Number of pages | 9 |
| Journal | The Lancet |
| Volume | 383 |
| Issue number | 9933 |
| DOIs | |
| Publication status | Published (VoR) - 2014 |
Funding
This work was done as part of the Cardiogenics Project, which is funded by the European Union ( LSHM-CT 2006–037593 ). The MARTHA project was supported by a grant from the Program Hospitalier de Recherche Clinique, and the methylation array typing was funded by the Canadian Institutes of Health Research ( grant MOP 86466 ) and the Heart and Stroke Foundation of Canada ( grant T6484 ). Statistical analyses of the MARTHA datasets were done in the C2BIG computing centre (UPMC, Paris, France), which is funded by the Fondation pour la Recherche Médicale and Région Ile de France. The KORA study was initiated and financed by the Helmholtz Zentrum München—German Research Center for Environmental Health, which is funded by the German Federal Ministry of Education and Research and by the State of Bavaria. The MuTHER study was funded by a programme grant from the Wellcome Trust ( 081917/Z/07/Z ), and receives support from the National Institute for Health Research BioResource Clinical Research Facility and Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London. CPN is funded by the National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, and this work comes under the portfolio of translational research supported by this unit. DA was supported by a PhD grant from the Région Ile de France (CORDDIM). FG holds a Canada Research Chair. JE, FC, HS, D-AT, and NJS collaborate under a Fondation Leducq Grant ( 12CVD02 ). TDS is a European Research Council Senior Investigator and is holder of an ERC Advanced Principal Investigator award. PD is supported by the Wellcome Trust core grant to the Wellcome Trust Sanger Institute ( 098051 ), which funded DNA methylation analysis for MuTHER. NJS holds a chair funded by the British Heart Foundation and is a National Institute for Health Research Senior Investigator. We thank the staff from the genotyping facilities at the Wellcome Trust Sanger Institute for sample preparation, quality control, and typing for the Cardiogenics and MuTHER cohorts.