Effect of negative pressure wound therapy vs standard wound management on 12-month disability among adults with severe open fracture of the lower limb the wollf randomized clinical trial

TY - JOUR

T1 - Effect of negative pressure wound therapy vs standard wound management on 12-month disability among adults with severe open fracture of the lower limb the wollf randomized clinical trial

AU - for the UK WOLLF Collaboration

AU - Costa, Matthew L.

AU - Achten, Juul

AU - Bruce, Julie

AU - Tutton, Elizabeth

AU - Petrou, Stavros

AU - Lamb, Sarah E.

AU - Parsons, Nick R.

AU - Rogers, Benedict

AU - Willett, Include Keith

AU - Griffin, Damian

AU - Jeffery, Steven

AU - Arrowsmith, Jill

AU - Datta, Gorav

AU - Dennison, Mick

AU - Farrar, Mark

AU - Giannoudis, Peter

AU - Gray, Andrew

AU - Henman, Philip

AU - Hull, Peter

AU - Khan, Umraz

AU - Lewis, Charlotte

AU - Loveday, David

AU - Mangwani, Jitendra

AU - McAndrew, Andrew

AU - McClelland, Damian

AU - McNicholas, Mike

AU - Noyes, David

AU - Ollivere, Ben

AU - Pallister, Ian

AU - Porter, Keith

AU - Ramachandran, Manoj

AU - Rickard, Rory

AU - Sharma, Hemant

AU - Tavakkolizadeh, Adel

AU - Young, Jonathan

N1 - Funding Information: completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Costa reported receiving a grant from the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) and is a member of its general board. Dr Achten reported receiving grants from the NIHR. Dr Lamb reported receiving grants from NIHR HTA and being a member of the NIHR HTA Additional Capacity Funding Board, HTA end of life care and add-on studies, HTA Prioritisation Group, and HTA Trauma Board. Dr Parsons reported receiving grants from the University of Warwick. No other disclosures were reported. Funding Information: Funding/Support: This project was funded by the UK NIHR HTA Programme (project No. 10/57/20) and was supported by the NIHR Oxford Biomedical Research Centre and the NIHR Collaboration for Leadership in Applied Health Research and Care in Oxford. The 2 main commercial entities (Smith & Nephew and KCI Medical) in this sector funded the excess treatment costs of the negative pressure wound therapy dressings but had no part in the design, conduct, or reporting of the trial. Publisher Copyright: © 2018 American Medical Association. All rights reserved.

PY - 2018/6/12

Y1 - 2018/6/12

UR - http://www.scopus.com/inward/record.url?scp=85048566430&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048566430&partnerID=8YFLogxK

U2 - 10.1001/jama.2018.6452

DO - 10.1001/jama.2018.6452

M3 - Article

C2 - 29896626

AN - SCOPUS:85048566430

SN - 0098-7484

VL - 319

SP - 2280

EP - 2288

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

IS - 22

ER -