Effects of zinc, vitamin D, and their co-supplementation on mood, serum cortisol, and brain-derived neurotrophic factor in patients with obesity and mild to moderate depressive symptoms: A phase II, 12-wk, 2 × 2 factorial design, double-blind, randomized, placebo-controlled trial

Somaye Yosaee, Sepideh Soltani, Alireza Esteghamati, Seyed Abbas Motevalian, Mehdi Tehrani-Doost, Cain C.T. Clark, Shima Jazayeri*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    26 Citations (SciVal)
    Original languageEnglish
    Article number110601
    JournalNutrition
    Volume71
    DOIs
    Publication statusPublished (VoR) - Mar 2020

    Funding

    This study was performed according to the principles of the Declaration of Helsinki, and the study protocol was approved by the institutional ethics committee of Iran University of Medical Sciences (IR.IUMS.REC 1395.9221324205). The study protocol was carefully explained to all participants signing an informed consent form. This trial was registered on the Iranian website ( www.irct.ir ) for registration of clinical trials ( http://www.irct.ir: IRCT201601252394 N31- 31-10-2016). The project was financially supported by Iran University of Medical Sciences.

    FundersFunder number
    Iran University of Medical Sciences

      Keywords

      • BDNF
      • Cortisol
      • Depression
      • Obesity

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