Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

TY - JOUR

T1 - Global, regional, and national burden of neurological disorders, 1990–2016

T2 - a systematic analysis for the Global Burden of Disease Study 2016

AU - GBD 2016 Neurology Collaborators

AU - Feigin, Valery L.

AU - Nichols, Emma

AU - Alam, Tahiya

AU - Bannick, Marlena S.

AU - Beghi, Ettore

AU - Blake, Natacha

AU - Culpepper, William J.

AU - Dorsey, E. Ray

AU - Elbaz, Alexis

AU - Ellenbogen, Richard G.

AU - Fisher, James L.

AU - Fitzmaurice, Christina

AU - Giussani, Giorgia

AU - Glennie, Linda

AU - James, Spencer L.

AU - Johnson, Catherine Owens

AU - Kassebaum, Nicholas J.

AU - Logroscino, Giancarlo

AU - Marin, Benoît

AU - Mountjoy-Venning, W. Cliff

AU - Nguyen, Minh

AU - Ofori-Asenso, Richard

AU - Patel, Anoop P.

AU - Piccininni, Marco

AU - Roth, Gregory A.

AU - Steiner, Timothy J.

AU - Stovner, Lars Jacob

AU - Szoeke, Cassandra E.I.

AU - Theadom, Alice

AU - Vollset, Stein Emil

AU - Wallin, Mitchell Taylor

AU - Wright, Claire

AU - Zunt, Joseph Raymond

AU - Abbasi, Nooshin

AU - Abd-Allah, Foad

AU - Abdelalim, Ahmed

AU - Abdollahpour, Ibrahim

AU - Aboyans, Victor

AU - Abraha, Haftom Niguse

AU - Acharya, Dilaram

AU - Adamu, Abdu A.

AU - Adebayo, Oladimeji M.

AU - Adeoye, Abiodun Moshood

AU - Adsuar, Jose C.

AU - Afarideh, Mohsen

AU - Agrawal, Sutapa

AU - Ahmadi, Alireza

AU - Ahmed, Muktar Beshir

AU - Aichour, Amani Nidhal

AU - Aremu, Olatunde

N1 - Funding Information: CATA reports personal fees from Johnson & Johnson (Philippines), outside the submitted work. JÄ reports lecturing fees from AstraZeneca, outside the submitted work. YB reports personal fees from AstraZeneca, Boehringer Ingelheim, Daiichi-Sankyo, Bristol-Myers Squibb (BMS), Pfizer, Medtronic, Bayer, Novex Pharma, Merck Sharp & Dohme (MSD), and grants from AstraZeneca and Boehringer Ingelheim, outside the submitted work. CC reports personal fees from Alliance for Better Bone Health, Amgen, Eli Lilly, GlaxoSmithKline (GSK), Medtronic, Merck, Novartis, Pfizer, Roche, Servier, Takeda, and UCB, outside the submitted work. JJJ reports grants and personal fees from Valeant, personal fees from ALAB Laboratoria and Amgen, and non-financial support from Microlife and Servier, outside the submitted work. ASK reports grants from SanBio and Biogen, personal fees from Neuravi, and other financial support from Sanofi, outside the submitted work. SLo reports personal fees from Amgen, Berlin-Chemie, MSD, Novo Nordisk, Sanofi-Aventis, Synlab, Unilever, and non-financial support from Preventicus, outside the submitted work; SLo is a member of the Scientific Board of the German Nutrition Society and a co-author of the evidence-based guideline Fat Intake and Prevention of Nutrition-Related Diseases published by the German Nutrition Society. WMä reports grants and personal fees from Siemens Diagnostics, Aegerion Pharmaceuticals, Amgen, AstraZeneca, Danone Research, Pfizer, BASF, Numares AG, and Berlin-Chemie, personal fees from Hoffmann LaRoche, MSD, Sanofi, and Synageva, grants from Abbott Diagnostics, and other financial support from Synlab Holding Deutschland GmbH, outside the submitted work. GVP reports personal fees from Shire, Teva, Medice, and Editora Manole, outside the submitted work. MJP reports grants and personal fees from Sigma Tau, MSD, GSK, Pfizer, Boehringer Ingelheim, Novavax, Ingress Health, AbbVie, and Sanofi, grants from AstraZeneca, ARTEG, Mundipharma, Bayer, and BMS; personal fees from Quintiles, Astellas, Mapi, OptumInsight, Novartis, Swedish Orphan, Innoval, Janssen, Intercept, and Pharmerit, other financial relationships with Ingress Health and PAG Ltd, and grants, personal fees, non-financial support, and other relationships with Asc Academics, outside the submitted work. RAS is the Chair of the ICD11 Neuroscience Topic Advisory Group and the past president of the World Federation of Neurology. JAS reports consulting activities with Horizon, Fidia, UBM LLC, Medscape, WebMD, the National Institutes of Health and the American College of Rheumatology, serves as the principal investigator for an investigator-initiated study funded by Horizon pharmaceuticals through a grant to DINORA Inc, a 501c3 entity, and is on the steering committee of OMERACT, an international organisation that develops measures for clinical trials and receives funding from 12 pharmaceutical companies (Amgen, Janssen, Novartis, Roche, UCB Group, Ardea/AstraZeneca, BMS, Celgene, Eli Lilly, Horizon Pharma, Pfizer, and Centrexion). AGT reports grants from National Health and Medical Research Council (NHMRC), Australia, during the conduct of the study, and grants from NHMRC, outside the submitted work. All other authors declare no competing interests. Funding Information: ROA is funded by the National Institutes of Health (U01HG010273). SMA acknowledges the International Centre for Casemix and Clinical Coding, Faculty of Medicine, National University of Malaysia and Department of Health Policy and Management, Faculty of Public Health, Kuwait University for the approval and support to participate in this research project. AAw acknowledges funding support from Department of Science and Technology, Government of India, New Delhi, through INSPIRE Faculty scheme. TBA acknowledges partial funding from the Institute of Medical Research and Medicinal Plant Studies. ABa is supported by the Public Health Agency of Canada. TWB was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor Award, funded by the Federal Ministry of Education and Research. MSBS acknowledges support from the Australian Government Research and Training Program scholarship for a PhD degree at the Australian National University, Australia. JJC is supported by the Swedish Heart and Lung Foundation. FCar is supported by the European Union (FEDER funds POCI/01/0145/FEDER/007728 and POCI/01/0145/FEDER/007265 ) and National Funds (FCT/MEC, Fundação para a Ciência e a Tecnologia and Ministério da Educação e Ciência) under the Partnership Agreements PT2020 UID/MULTI/04378/2013 and PT2020UID/QUI/50006/2013. EC is supported by an Australian Research Council Future Fellowship ( FT3 140100085 ). KD is supported by a Wellcome Trust [ Grant Number 201900 ] as part of his International Intermediate Fellowship. EF is supported by the European Union (FEDER funds POCI/01/0145/FEDER/007728 and POCI/01/0145/FEDER/007265 ) and National Funds (FCT/MEC, Fundação para a Ciência e a Tecnologia and Ministério da Educação e Ciência) under the Partnership Agreements PT2020 UID/MULTI/04378/2013 and PT2020UID/QUI/50006/2013 . SMSI is funded by the Institute for Physical Activity and Nutrition (IPAN), Deakin University and received funding from High Blood Pressure Research Council of Australia. YKa is a DBT/Wellcome Trust India Alliance Fellow in Public Health. YJK is supported by the Office of Research and Innovation at Xiamen University Malaysia. BL acknowledges funding from the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. WDL is supported in part by U10NS086484 NINDS. SLo is funded by the German Federal Ministry of Education and Research (nutriCARD, grant agreement number 01EA1411A). RML is supported by a National Health and Medical Research Council (NHMRC) of Australia Senior Research Fellowship. AMa and the Imperial College London are grateful for support from the NW London NIHR Collaboration for Leadership in Applied Health Research and Care. JJM is supported by the Danish National Research Foundation (Niels Bohr Professorship), and the John Cade Fellowship ( APP1056929 ) from NHMRC. TMei acknowledges additional institutional support from the Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD), Jena-Halle-Leipzig. IMV is supported by the Sistema Nacional de Investigación (Panama). MOO is supported by SIREN U54 U54HG007479 and SIBS Genomics R01NS107900 grants. AMS was supported by a fellowship from the Egyptian Fulbright Mission Program. MMSM acknowledges the support from the Ministry of Education, Science and Technological Development, Republic of Serbia (contract no 175087). AShe is supported by Health Data Research UK. MBS' work on traumatic brain injury is supported by grants NIH U01 NS086090 (PI G Manley) from the National Institutes of Health (NIH) and DoD W81XWH-14–2-0176 (PI G Manley) from the United States Department of Defense. RTS is supported in part by grant number PROMETEOII/2015/021 from Generalitat Valenciana and the national grant PI17/00719 from ISCIII-FEDER. AGT was supported by a Fellowship from the NHMRC (Australia; 1042600. KBT acknowledges funding supports from the Maurice Wilkins Centre for Biodiscovery, Cancer Society of New Zealand, Health Research Council, Gut Cancer Foundation, and the University of Auckland. CY acknowledges support from the National Natural Science Foundation of China (grant number 81773552 ) and the Chinese NSFC International Cooperation and Exchange Program (grant number 71661167007 ). Publisher Copyright: © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

PY - 2019/5/1

Y1 - 2019/5/1

UR - http://www.scopus.com/inward/record.url?scp=85064086327&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85064086327&partnerID=8YFLogxK

U2 - 10.1016/S1474-4422(18)30499-X

DO - 10.1016/S1474-4422(18)30499-X

M3 - Article

C2 - 30879893

AN - SCOPUS:85064086327

SN - 1474-4422

VL - 18

SP - 459

EP - 480

JO - The Lancet Neurology

JF - The Lancet Neurology

IS - 5

ER -