Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation

Masahiko Kagoshima; Torgny Wilcke; Kazuhiro Ito; Loukia Tsaprouni; Peter J. Barnes; Neville Punchard; Ian M. Adcock

doi:10.1016/S0014-2999(01)01332-2

Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation

Masahiko Kagoshima
, Torgny Wilcke
, Kazuhiro Ito
, Loukia Tsaprouni
, Peter J. Barnes
, Neville Punchard
, Ian M. Adcock^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

72 Citations (SciVal)

Original language	English
Pages (from-to)	327-334
Number of pages	8
Journal	European Journal of Pharmacology
Volume	429
Issue number	1-3
DOIs	https://doi.org/10.1016/S0014-2999(01)01332-2
Publication status	Published (VoR) - 10 Oct 2001

Funding

This work was funded by research grants from the Clinical Research Committee (Royal Brompton Hospital) and Schering Plough (USA). We would like to thank Professor R.H. Goodman (Portland, OR) for the murine CBP cDNA, Dr. L.M. Schmitz (Vienna, Austria) for the p65 and the 6× κB-Luc cDNA and Dr. K. Nolop (Schering-Plough, Kenilworth, NJ) for the provision of mometasone furoate. T.W. is funded by an Astra (Denmark) Research Fellowship.

Keywords

CREB binding protein
DNA methylation
Glucocorticoid receptor
Histone acetylation
Inflammation
NF-κB (Nuclear factor kappaB)

Access to Document

10.1016/S0014-2999(01)01332-2

Cite this

@article{9271f1dfb0f9445082569ce415671a68,

title = "Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation",

keywords = "CREB binding protein, DNA methylation, Glucocorticoid receptor, Histone acetylation, Inflammation, NF-κB (Nuclear factor kappaB)",

author = "Masahiko Kagoshima and Torgny Wilcke and Kazuhiro Ito and Loukia Tsaprouni and Barnes, \{Peter J.\} and Neville Punchard and Adcock, \{Ian M.\}",

note = "Funding Information: This work was funded by research grants from the Clinical Research Committee (Royal Brompton Hospital) and Schering Plough (USA). We would like to thank Professor R.H. Goodman (Portland, OR) for the murine CBP cDNA, Dr. L.M. Schmitz (Vienna, Austria) for the p65 and the 6× κB-Luc cDNA and Dr. K. Nolop (Schering-Plough, Kenilworth, NJ) for the provision of mometasone furoate. T.W. is funded by an Astra (Denmark) Research Fellowship.",

year = "2001",

month = oct,

day = "10",

doi = "10.1016/S0014-2999(01)01332-2",

language = "English",

volume = "429",

pages = "327--334",

journal = "European Journal of Pharmacology",

issn = "0014-2999",

publisher = "Elsevier",

number = "1-3",

}

TY - JOUR

T1 - Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation

AU - Kagoshima, Masahiko

AU - Wilcke, Torgny

AU - Ito, Kazuhiro

AU - Tsaprouni, Loukia

AU - Barnes, Peter J.

AU - Punchard, Neville

AU - Adcock, Ian M.

N1 - Funding Information: This work was funded by research grants from the Clinical Research Committee (Royal Brompton Hospital) and Schering Plough (USA). We would like to thank Professor R.H. Goodman (Portland, OR) for the murine CBP cDNA, Dr. L.M. Schmitz (Vienna, Austria) for the p65 and the 6× κB-Luc cDNA and Dr. K. Nolop (Schering-Plough, Kenilworth, NJ) for the provision of mometasone furoate. T.W. is funded by an Astra (Denmark) Research Fellowship.

PY - 2001/10/10

Y1 - 2001/10/10

KW - CREB binding protein

KW - DNA methylation

KW - Glucocorticoid receptor

KW - Histone acetylation

KW - Inflammation

KW - NF-κB (Nuclear factor kappaB)

UR - https://www.scopus.com/pages/publications/0035840839

UR - https://www.scopus.com/pages/publications/0035840839#tab=citedBy

U2 - 10.1016/S0014-2999(01)01332-2

DO - 10.1016/S0014-2999(01)01332-2

M3 - Article

C2 - 11698053

AN - SCOPUS:0035840839

SN - 0014-2999

VL - 429

SP - 327

EP - 334

JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

IS - 1-3

ER -

Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation

Funding

Keywords

Access to Document

Other files and links

Fingerprint

Cite this