Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

Tara Hurst; Matthew Pace; Aris Katzourakis; Rodney Phillips; Paul Klenerman; John Frater; Gkikas Magiorkinis

doi:10.1186/s12977-016-0242-4

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

Tara Hurst
, Matthew Pace
, Aris Katzourakis
, Rodney Phillips
, Paul Klenerman
, John Frater^*
, Gkikas Magiorkinis

^*Corresponding author for this work

University of Oxford
John Radcliffe Hospital
University of New South Wales

Research output: Contribution to journal › Article › peer-review

28 Citations (SciVal)

Original language	English
Article number	10
Journal	Retrovirology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1186/s12977-016-0242-4
Publication status	Published (VoR) - 6 Feb 2016

Funding

TH and GM are supported by an MRC Clinician Scientist Fellowship awarded to GM. AK is supported by a Royal Society University Research Fellowship. JF is supported by a MRC Senior Clinical Fellowship, the Oxford Martin School and the Oxford NIHR Comprehensive Biomedical Research Centre.

Keywords

Endogenous retroviruses
HDAC inhibitors
HERV-K (HML-2)
HIV-1 cure
HIV-1 latency

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10.1186/s12977-016-0242-4

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AU - Hurst, Tara

AU - Pace, Matthew

AU - Katzourakis, Aris

AU - Phillips, Rodney

AU - Klenerman, Paul

AU - Frater, John

AU - Magiorkinis, Gkikas

N1 - Funding Information: TH and GM are supported by an MRC Clinician Scientist Fellowship awarded to GM. AK is supported by a Royal Society University Research Fellowship. JF is supported by a MRC Senior Clinical Fellowship, the Oxford Martin School and the Oxford NIHR Comprehensive Biomedical Research Centre. Publisher Copyright: © 2016 Hurst et al.

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KW - Endogenous retroviruses

KW - HDAC inhibitors

KW - HERV-K (HML-2)

KW - HIV-1 cure

KW - HIV-1 latency

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UR - https://www.scopus.com/pages/publications/84957806519#tab=citedBy

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Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

Funding

Keywords

Access to Document

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