Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ss DNA targets: An evolutionary hypothesis for antiretroviral checkpoint

Tara Patricia Hurst; Amr Aswad; Timokratis Karamitros; Aris Katzourakis; Adrian L. Smith; Gkikas Magiorkinis

doi:10.3389/fmicb.2019.01426

Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ss DNA targets: An evolutionary hypothesis for antiretroviral checkpoint

Tara Patricia Hurst^*
, Amr Aswad
, Timokratis Karamitros
, Aris Katzourakis
, Adrian L. Smith
, Gkikas Magiorkinis

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (SciVal)

Original language	English
Article number	1426
Journal	Frontiers in Microbiology
Volume	10
Issue number	JULY
DOIs	https://doi.org/10.3389/fmicb.2019.01426
Publication status	Published (VoR) - 2019

Funding

TH, TK, and GM were supported by an MRC Clinician Scientist Fellowship awarded to GM (MR/K010565/1). AK was supported by the Royal Society.

Keywords

Checkpoint
Endogenous retrovirus
Evolution
IFI16
SsDNA

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10.3389/fmicb.2019.01426

Cite this

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title = "Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ss DNA targets: An evolutionary hypothesis for antiretroviral checkpoint",

keywords = "Checkpoint, Endogenous retrovirus, Evolution, IFI16, SsDNA",

author = "Hurst, \{Tara Patricia\} and Amr Aswad and Timokratis Karamitros and Aris Katzourakis and Smith, \{Adrian L.\} and Gkikas Magiorkinis",

note = "Funding Information: TH, TK, and GM were supported by an MRC Clinician Scientist Fellowship awarded to GM (MR/K010565/1). AK was supported by the Royal Society. Publisher Copyright: {\textcopyright} 2019 Hurst, Aswad, Karamitros, Katzourakis, Smith and Magiorkinis.",

year = "2019",

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language = "English",

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T1 - Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ss DNA targets

T2 - An evolutionary hypothesis for antiretroviral checkpoint

AU - Hurst, Tara Patricia

AU - Aswad, Amr

AU - Karamitros, Timokratis

AU - Katzourakis, Aris

AU - Smith, Adrian L.

AU - Magiorkinis, Gkikas

N1 - Funding Information: TH, TK, and GM were supported by an MRC Clinician Scientist Fellowship awarded to GM (MR/K010565/1). AK was supported by the Royal Society. Publisher Copyright: © 2019 Hurst, Aswad, Karamitros, Katzourakis, Smith and Magiorkinis.

PY - 2019

Y1 - 2019

KW - Checkpoint

KW - Endogenous retrovirus

KW - Evolution

KW - IFI16

KW - SsDNA

UR - https://www.scopus.com/pages/publications/85069482429

UR - https://www.scopus.com/pages/publications/85069482429#tab=citedBy

U2 - 10.3389/fmicb.2019.01426

DO - 10.3389/fmicb.2019.01426

M3 - Article

AN - SCOPUS:85069482429

SN - 1664-302X

VL - 10

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

IS - JULY

M1 - 1426

ER -

Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ss DNA targets: An evolutionary hypothesis for antiretroviral checkpoint

Funding

Keywords

Access to Document

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