Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK

Refik Kuburas; Mayel Gharanei; Irmgard Haussmann; Helen Maddock; Hardip Sandhu

doi:10.1097/FJC.0000000000001256

Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK

Refik Kuburas
, Mayel Gharanei
, Irmgard Haussmann
, Helen Maddock
, Hardip Sandhu^*

^*Corresponding author for this work

Coventry University

Research output: Contribution to journal › Article › peer-review

10 Citations (SciVal)

Original language	English
Pages (from-to)	799-807
Number of pages	9
Journal	Journal of Cardiovascular Pharmacology
Volume	79
Issue number	6
DOIs	https://doi.org/10.1097/FJC.0000000000001256
Publication status	Published (VoR) - 23 Jun 2022

Funding

Supported by Coventry University, Faculty of Sport, Exercise and Life Sciences.

Keywords

AMP-protein kinase
Cardiac myocytes
Cardioprotection
Cardiotoxicity
Metformin
Sunitinib

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10.1097/FJC.0000000000001256

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title = "Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK",

keywords = "AMP-protein kinase, Cardiac myocytes, Cardioprotection, Cardiotoxicity, Metformin, Sunitinib",

author = "Refik Kuburas and Mayel Gharanei and Irmgard Haussmann and Helen Maddock and Hardip Sandhu",

note = "Funding Information: Supported by Coventry University, Faculty of Sport, Exercise and Life Sciences. Publisher Copyright: {\textcopyright} 2022 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.",

year = "2022",

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T1 - Metformin Protects Against Sunitinib-induced Cardiotoxicity

T2 - Investigating the Role of AMPK

AU - Kuburas, Refik

AU - Gharanei, Mayel

AU - Haussmann, Irmgard

AU - Maddock, Helen

AU - Sandhu, Hardip

N1 - Funding Information: Supported by Coventry University, Faculty of Sport, Exercise and Life Sciences. Publisher Copyright: © 2022 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.

PY - 2022/6/23

Y1 - 2022/6/23

KW - AMP-protein kinase

KW - Cardiac myocytes

KW - Cardioprotection

KW - Cardiotoxicity

KW - Metformin

KW - Sunitinib

UR - https://www.scopus.com/pages/publications/85131701847

UR - https://www.scopus.com/pages/publications/85131701847#tab=citedBy

U2 - 10.1097/FJC.0000000000001256

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M3 - Article

C2 - 35266920

AN - SCOPUS:85131701847

SN - 0160-2446

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JO - Journal of Cardiovascular Pharmacology

JF - Journal of Cardiovascular Pharmacology

IS - 6

ER -

Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK

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