Mitoparan and target-selective chimeric analogues: Membrane translocation and intracellular redistribution induces mitochondrial apoptosis

Sarah Jones*, Cecile Martel, Anne Sophie Belzacq-Casagrande, Catherine Brenner, John Howl

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    49 Citations (SciVal)
    Original languageEnglish
    Pages (from-to)849-863
    Number of pages15
    JournalBiochimica et Biophysica Acta - Molecular Cell Research
    Volume1783
    Issue number5
    DOIs
    Publication statusPublished (VoR) - May 2008

    Funding

    We are indebted to Keith Holding for his outstanding technical assistance. J. Howl and S. Jones and would also like to thank the Samantha Dickson Brain Tumour Trust for their financial support. C. Brenner is supported by grants funded by Agence Nationale pour la Valorisation de la Recherche (ANVAR), n°A0505001, Association pour la recherche sur le Cancer (ARC) and by the Institut National du Cancer (INCa, n°0610-3D1616-123/PL-2006).

    FundersFunder number
    Appalachian Regional Commission
    Association pour la Recherche sur le Cancer
    Samantha Dickson Brain Tumour Trust
    Agence Nationale de la RechercheA0505001
    Institut National Du Cancer0610-3D1616-123/PL-2006

      Keywords

      • Apoptosis
      • Cell penetrating peptides
      • Chimerism
      • Mastoparan
      • Mitochondria

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