Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial)

UK Dermatology Clinical Trials Network’s CLOTHES Trial Team

    Research output: Contribution to journalArticlepeer-review

    41 Citations (SciVal)
    Original languageEnglish
    Article numbere1002280
    JournalPLoS Medicine
    Volume14
    Issue number4
    DOIs
    Publication statusPublished (VoR) - 2017

    Funding

    The trial was sponsored by the University of Nottingham, was coordinated from the Nottingham Clinical Trials Unit, and was supported by the National Institute for Health Research Clinical Research Network. The trial was developed with support from the UK Dermatology Clinical Trials Network. I have read the journal's policy and the authors of this manuscript have the following competing interests: KST, LEB, THS, JMB, SL, EFH, RHH, HCW, TD, NPB, IP, JL, CC, JDG, JG, EJM, FC and AAM received grants from NIHR Health Technology Assessment Programme (11/65/01), for the conduct of this study. KT reports silk garments for use in the trial were donated by Espère Healthcare Ltd. (UK and Ireland distributor for DermaSilk™, AlPreTec SrL. Italy) and DreamSkin Health Ltd. SL reports receiving an honorarium from Thornton & Ross and Bayer for educational activities outside the submitted work. HCW is Director of the NIHR Health Technology Assessment Programme. SJB reports grants from Wellcome Trust during the conduct of the study; personal fees from American Academy of Asthma Allergy and Immunology, outside the submitted work; In addition, SJB has a patent GB 1602011.7 pending (outside the submitted work). THS holds a Career Development Fellowship (NIHR-2014-07-006) supported by the National Institute for Health Research. AG reports salary support from Clinical Research Network and non-financial support from NCTU, outside the submitted work. Representatives of Espère Healthcare Ltd. and DreamSkin Health Ltd provided technical advice on how to use the garments. However, they played no role in the analysis or interpretation of the trial findings.

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