Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS)

Victoria Hodgetts-Morton; Catherine A. Hewitt; Amie Wilson; Nicola Farmer; Annalise Weckesser; Emily Dixon; Peter Brocklehurst; Pollyanna Hardy; Rachel K. Morris

doi:10.1111/aogs.13737

Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS)

Victoria Hodgetts-Morton, Catherine A. Hewitt, Amie Wilson, Nicola Farmer, Annalise Weckesser, Emily Dixon, Peter Brocklehurst, Pollyanna Hardy, Rachel K. Morris^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (SciVal)

Original language	English
Pages (from-to)	231-239
Number of pages	9
Journal	Acta Obstetricia et Gynecologica Scandinavica
Volume	99
Issue number	2
DOIs	https://doi.org/10.1111/aogs.13737
Publication status	Published (VoR) - 1 Feb 2020

Funding

Funding Information This paper presents independent research funded by the National Institute for Health Research (NIHR) under the Research for Patient Benefit (RfPB) Programe (Grant Reference Number PB-PG-1215-20013). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health and Social Care. The funder had no role in conducting the research or writing the paper.Key MessageA randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. A randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. We would like to acknowledge the research teams, principal investigators and lead research midwives at the recruiting sites: Birmingham Women?s and Children?s Hospital, Birmingham Heartlands Hospital (Dr. Sharon Morad and Lucy O?Leary), Princess Royal Hospital Telford (Dr. Sheena Hodgett and Helen Millward) and Sunderland Royal Hospital (Mr. Kim Hinshaw and Gill Campbell). We would like to also thank Lee Middleton and Jane Daniels who provided methodological support during the funding application. An independent trial steering committee was appointed to oversee the trial and met regularly throughout the trial; we would like to thank Dr. Jennifer Myers, Dr. Stephen Kaey, and Elaine Stamp for their oversight.

Keywords

cesarean section
chlorhexidine
endometritis
pilot projects
sepsis
surgical wound infection
vaginal cleansing
vaginal douching

Access to Document

10.1111/aogs.13737

Cite this

Hodgetts-Morton, V., Hewitt, C. A., Wilson, A., Farmer, N., Weckesser, A., Dixon, E., Brocklehurst, P., Hardy, P., & Morris, R. K. (2020). Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS). Acta Obstetricia et Gynecologica Scandinavica, 99(2), 231-239. https://doi.org/10.1111/aogs.13737

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author = "Victoria Hodgetts-Morton and Hewitt, \{Catherine A.\} and Amie Wilson and Nicola Farmer and Annalise Weckesser and Emily Dixon and Peter Brocklehurst and Pollyanna Hardy and Morris, \{Rachel K.\}",

note = "Funding Information: Funding Information This paper presents independent research funded by the National Institute for Health Research (NIHR) under the Research for Patient Benefit (RfPB) Programe (Grant Reference Number PB-PG-1215-20013). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health and Social Care. The funder had no role in conducting the research or writing the paper.Key MessageA randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. A randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. We would like to acknowledge the research teams, principal investigators and lead research midwives at the recruiting sites: Birmingham Women?s and Children?s Hospital, Birmingham Heartlands Hospital (Dr. Sharon Morad and Lucy O?Leary), Princess Royal Hospital Telford (Dr. Sheena Hodgett and Helen Millward) and Sunderland Royal Hospital (Mr. Kim Hinshaw and Gill Campbell). We would like to also thank Lee Middleton and Jane Daniels who provided methodological support during the funding application. An independent trial steering committee was appointed to oversee the trial and met regularly throughout the trial; we would like to thank Dr. Jennifer Myers, Dr. Stephen Kaey, and Elaine Stamp for their oversight. Publisher Copyright: {\textcopyright} 2019 Nordic Federation of Societies of Obstetrics and Gynecology",

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doi = "10.1111/aogs.13737",

language = "English",

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Hodgetts-Morton, V, Hewitt, CA, Wilson, A, Farmer, N, Weckesser, A, Dixon, E, Brocklehurst, P, Hardy, P & Morris, RK 2020, 'Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS)', Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 2, pp. 231-239. https://doi.org/10.1111/aogs.13737

TY - JOUR

T1 - Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis

T2 - A randomized pilot trial (PREPS)

AU - Hodgetts-Morton, Victoria

AU - Hewitt, Catherine A.

AU - Wilson, Amie

AU - Farmer, Nicola

AU - Weckesser, Annalise

AU - Dixon, Emily

AU - Brocklehurst, Peter

AU - Hardy, Pollyanna

AU - Morris, Rachel K.

N1 - Funding Information: Funding Information This paper presents independent research funded by the National Institute for Health Research (NIHR) under the Research for Patient Benefit (RfPB) Programe (Grant Reference Number PB-PG-1215-20013). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health and Social Care. The funder had no role in conducting the research or writing the paper.Key MessageA randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. A randomized controlled trial of vaginal cleansing with an antiseptic solution before elective and emergency cesarean section is feasible. We would like to acknowledge the research teams, principal investigators and lead research midwives at the recruiting sites: Birmingham Women?s and Children?s Hospital, Birmingham Heartlands Hospital (Dr. Sharon Morad and Lucy O?Leary), Princess Royal Hospital Telford (Dr. Sheena Hodgett and Helen Millward) and Sunderland Royal Hospital (Mr. Kim Hinshaw and Gill Campbell). We would like to also thank Lee Middleton and Jane Daniels who provided methodological support during the funding application. An independent trial steering committee was appointed to oversee the trial and met regularly throughout the trial; we would like to thank Dr. Jennifer Myers, Dr. Stephen Kaey, and Elaine Stamp for their oversight. Publisher Copyright: © 2019 Nordic Federation of Societies of Obstetrics and Gynecology

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KW - endometritis

KW - pilot projects

KW - sepsis

KW - surgical wound infection

KW - vaginal cleansing

KW - vaginal douching

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Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS)

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REF2021 03Z_ICS_B: Complex and Multiple Birth: Enhancing guidance, practice and understanding

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Vaginal preparation with chlorhexidine at cesarean section to reduce endometritis and prevent sepsis: A randomized pilot trial (PREPS)

Funding

Keywords

Access to Document

Other files and links

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REF2021 03Z_ICS_B: Complex and Multiple Birth: Enhancing guidance, practice and understanding

Cite this